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Why Botox Injections Do not Work On Some People?

Why Botox Injections Do not Work On Some People?

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More and more young people are turning to Botox Injections (Kim Kardashian did it on TV!) accepting the risk of putting chemicals into their bodies, and paying a high price for perfect faces, but could Botox suddenly stop working after a few years of treatments?

Well, we are here to answer this question. So, if you want to know how are immune to Botox Injections keep reading this note.

But what if Botox simply doesn’t work for you? Some have had success with their first, second, and sometimes third treatments with Botox, only to reach a point where the effects are either greatly diminished or entirely absent. Others appear to be immune to the effects of Botox from the start.

What Researches say about being Immune to Botox?

“Studies have indicated that if people are injected with dosages of 100 units of Botox or more, the body will start to react against the product and increase antibody production,” says Dr. Alexiades. “This means that after subsequent injections, the Botox will stop working. Muscles will start to recover rapidly, and the muscles that you injected won’t react the way they did the first time.”

This immunity won’t happen overnight, and the frequency of the injections determinse when a person will become immune to them. But why does it take a few months or years? “As the antibody levels rise, more and more of the Botox is inactivated before it has a chance to be absorbed into the nerve endings,” says Dr. Alexiades. “As a result, with each re-injection, the Botox Injections takes less and less effect and the muscles recover more and more rapidly.”

For this reason people are turning to other methods and types of injections. “I have found that if someone is immune to Botox, they do respond to the shorter version of botulinum toxin A, the newer Dysport,” says Dr. Alexiades. “Dysport is a shorter protein and often works in people who are unresponsive to Botox. Another type of Botox, Xeomin, has just been approved by the FDA and will offer yet another alternative.”

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Why It’s So Frustrating When Botox Injections Doesn’t Work?

When Botox Doesn’t Work

It is a little-known fact that some people can become resistant to the effects of Botox. It was once thought that the product wasn’t working because of improper storage, or injector error involving not using the correct technique or dosage.

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The patient’s own antibodies were never questioned, and so the typical protocol at that point is to simply offer more injections. As a result, the immune patient then ends up spending even more money on a treatment that just doesn’t work for her. Here now the botox injections for migraines

What the Makers of Botox Say

being Immune to Botox Injections

Since the explosion of Botox use, researchers and doctors are realizing that resistance to Botox can develop and, even that there may be some who are completely immune to its effects. According to a representative from Allergan, the company that makes Botox:

“Occasionally some patients may develop an immune response to BOTOX/BOTOX Cosmetic that may reduce the effectiveness of treatment. This is because BOTOX/BOTOX Cosmetic is a protein complex, and in some patients, the body’s immune system may respond by producing “blocking” (or neutralizing) antibodies capable of inactivating the protein’s biological activity. You can also check botox injections for migraines follow up

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Antibody formation is more of a concern when patients must receive frequent injections or when it is used to treat medical conditions such as cervical dystonia that require higher doses. However, recent long-term studies have indicated immunogenicity to be a minor concern even with that treatment. Both the BOTOX/BOTOX Cosmetic labels (attached) advise that the potential for antibody formation may be minimized by injecting with the lowest effective dose given at the longest feasible intervals between injections.”

To put it plainly, Botox resistance (immunity) is does occur in some patients. According to those who do recognize the phenomenon of Botox resistance, the numbers are low — about 1% to 3% of patients who are injected will develop toxin-blocking antibodies. Still, with millions of Botox injections being given every year, this number is not insignificant.

To minimize the risk of becoming resistant, patients should be given the lowest possible effective dose (which is a good idea for safety’s sake anyway). There are also studies that are looking at how age and frequency of treatment may affect a person’s ability to develop Botox resistance.

What to Do If You Are Immune to Botox?

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Keep in mind that the success of Botox injections is in fact highly dependent on technique, and it is also entirely possible to get a “bad batch” that is less than fresh (and, therefore, less effective).

If you try Botox Injections and it doesn’t seem to work for you, talk to your doctor. He may be willing to inject you again for free if you didn’t get results the first time. If it happens again and you are still determined to have a line-free forehead, try seeing a different doctor.

If you still don’t get results, then you just may be one of those rare people who is “immune” to Botox. If that turns out to be the case, then you can thank your amazing immune system, and you could always try learning to accept and embrace those little expression lines, or you could consider trying one of the many alternatives to Botox. Read more also about botox injections for migraines


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